Washington, DC – In 2016, the Frank R. Lautenberg Chemical Safety for the 21st Century Act was passed, amending the Toxic Substances Control Act (TSCA), the Nation’s primary chemical management law, for the first time in 40 years. The amended TSCA included advances such as: mandatory requirements for EPA to evaluate existing chemicals with clear and enforceable deadlines, risk-based chemical assessments, increased public transparency for chemical information, and a consistent source of funding for EPA to carry out its responsibilities under the new law. EPA scientists are providing support for several important TSCA activities including: the development of New Approach Methods for alternative toxicity testing; implementing approaches for chemical pre-prioritization; improving exposure assessment for new and existing chemicals; and supporting ongoing chemical assessments.